程冰冰博士任生物医学工程学院常任轨助理教授、研究员、博导、独立课题组组长(PI)，聚焦超声转化研究实验室(Translational Research in Ultrasound THeranostics – TRUTH Lab) 主任，国际电气电子工程师协会高级会员(IEEE Senior Member)。程博士在美国德克萨斯大学西南医学中心 (UT Southwestern Medical Center) 和德克萨斯大学阿灵顿分校 (University of Texas at Arlington)获得生物医学工程博士学位。毕业后在德克萨斯大学西南医学中心放射科开展以聚焦超声技术及其临床转化为主的博士后研究工作。后受邀前往加拿大卡尔加里大学卡明医学院 (Cumming School of Medicine, University of Calgary) 和霍奇基斯脑研究所(Hotchkiss Brain Institute) 继续博士后研究，并担任MRgFUS Program脑部药物递送方向的科研主管。

程博士专注于以聚焦超声为核心的无创精准诊疗方法和设备研发，目前已在相关领域期刊和国际会议上累计发表同行评议论文和摘要60余篇，包括Ultrasonics Sonochemistry (IF 8.7), IEEE Transactions on Biomedical Engineering等领域权威期刊。获得2项授权美国发明专利，申请多项中国发明专利。数十次受邀在国际学术会议上作大会口头报告，担任IEEE IUS国际超声大会技术委员会（TPC）委员。2021年加入上海科技大学，入选上海市海外高层次人才计划，主持多项纵向和横向项目。

• 聚焦超声技术开发与应用：血脑屏障开放、神经调控、温热疗法等

• 超声治疗系统与关键部件研发

• 人工智能在聚焦超声中的应用

生物医学信号与系统I

图像引导治疗

生物医学工程导论

Member for associations or committees:

• IEEE IUS 国际超声大会技术委员会委员

• IEEE Senior Member

• 中国研究型医院学会微无创诊疗专业委员会常委

• 上海市生物医学工程学会核医学工程专业委员会委员

• 国家科技专家库

• 上海市科技专家库

• 阿尔兹海默病防治协会 (China Association for Alzheimer’s Disease) 

• International Society for Therapeutic Ultrasound (ISTU)

• The Society for Thermal Medicine (STM)

• Biomedical Engineering Society (BMES)

• The Optical Society of America (OSA)

• The International Society for Optical Engineering (SPIE)

Editorial board member:

• VIEW 期刊青年编委

• iRadiology 期刊青年编委

Reviewer for journals:

• Human Brain Mapping

• Advanced Science                                            

• Theranostics                                                    

• Nanotechnology                                               

• International Journal of Hyperthermia                           

• Annals of Biomedical Engineering                         

• Physics in Medicine and Biology  

• Scientific Reports                                            

• PLOS ONE                                                        

• IEEE Journal of Lightwave Technology                           

• Biomedical Physics and Engineering Express                         

• Sensors                                                    

• Applied Sciences                                                                      

• Journal of Current Drug Delivery

目前程博士在生物医学工程领域高水平期刊上发表 SCI 论文20余篇，代表性研究成果列出如下 (^*：通讯作者)：

• Z. Xu, X. Piao, M. Wang, S. Pichardo, and B. Cheng*, “Microbubble-enhanced transcranial MR-guided focused ultrasound brain hyperthermia: heating mechanism investigation using finite element method”, in Ultrasonics Sonochemistry, vol 107, p. 106889, 2024

• H. Dai, W. Li, Q. Wang, B. Cheng*, “Multiple instance learning-based prediction of blood-brain barrier opening outcomes induced focused ultrasound”, in IEEE Transactions on Biomedical Engineering, 2024, doi: 10.1109/TBME.2024.3509533

• M. Wang, Z. Xu, B. Cheng*, “Systematic review of phase aberration correction algorithms for transcranial focused ultrasound”, in iRadiology, vol 3, pp. 26-46, 2024

• S. Hong, X. Piao, X. Yao, Y. Fan, S. Tang, C. Lue, J. Yao, F. Yao, Y. Jian, B. Cheng*, Y. Pei, “Helmholtz resonant cavity based metasurface for ultrasonic focusing”, in Journal of Applied Physics, vol 136, p. 183101, 2024

• B. Cheng^*, C. Bing, T. H. Chu, S. Alzahrani, S. Pichardo, and B. G. Pike,“Simultaneous localized brain mild hyperthermia and blood-brain barrier opening via feedback-controlled transcranial MR-guided focused ultrasound and microbubbles”, in IEEE Transactions on Biomedical Engineering, vol 69, pp. 1880-1888, 2022

• B. Cheng, C. Bing, R. M. Staruch, S. Shaikh, M. Wodzak Staruch, D. Szczepanski, N. S. Williams, T. W. Laetsch, and R. Chopra, “The effect of injected dose on localized tumor accumulation and cardiac uptake of doxorubicin in a Vx2 rabbit tumor model using MR-HIFU mild hyperthermia and thermosensitive liposomes”, in International Journal of Hyperthermia, vol. 37, pp. 1052-1059, 2020

• B. Cheng^*, C. Bing, Y. Xi, B. Shah, A. A. Exner, and R. Chopra, “Influence of nanobubble concentration on blood-brain barrier opening using focused ultrasound under real-time acoustic feedback control”, in Ultrasound in Medicine and Biology, vol. 45, pp. 2174-2187, 2019

• B. Cheng, V. Bandi, S. Yu, F. D’Souza, K. Nguyen, Y. Hong, L. Tang, and B. Yuan, “The mechanisms and biomedical applications of an NIR BODIPY-based switchable fluorescent probe”, in International Journal of Molecular Sciences, vol. 18, no. 2, p. 384, 2017

• B. Cheng, V. Bandi, M-Y. Wei, Y. Pei, F. D’Souza, K. Nguyen, Y. Hong, and B. Yuan, “High-resolution ultrasound-switchable fluorescence imaging in centimeter-deep tissue phantoms with high signal-to-noise ratio and high sensitivity via novel contrast agents”, in PLOS ONE, vol. 11, no. 11, p. e0165963, 2016

• B. Cheng, M-Y. Wei, Y. Liu, H. Pitta, Z. Xie, Y. Hong, K. Nguyen, and B. Yuan, “Development of ultrasound-switchable fluorescence imaging contrast agents based on thermosensitive polymers and nanoparticles”, in IEEE Journal of Selected Topics in Quantum Electronics, vol. 20, no. 3, p. 6801214, 2014

论文链接：

https://scholar.google.com/citations?user=eVk6RwMAAAAJ&hl=en

聚焦超声转化研究实验室(Translational Research in Ultrasound THeranostics—TRUTH Lab)致力于研发以聚焦超声为核心的无创精准诊疗方法和设备，涵盖基础科学和临床转化研究。研究领域属于多学科交叉（生物医学工程、电子信息、生物医药等），能够给有志于科研的学生和科研人员提供良好的研究条件和指导。丰富的研究方向也将为实验室成员提供广阔的发展空间。

实验室主要开展以下几方面的研究：

• 聚焦超声应用和技术创新，包括血脑屏障开放、神经调控以及温热疗法等

• 研发超声治疗系统及其关键部件，包括智能医疗机器人等

• 探索人工智能在聚焦超声中的应用，包括治疗过程优化、效果评估等

• 图像引导治疗，包括磁共振引导聚焦超声药物递送、热疗等