程冰冰
助理教授、研究员、博导
研究方向:智能医学、智慧仪器
办公室:生物医学工程学院大楼320房间
电话:
个人主页:
个人简历
研究领域
教学与课程
学术任职
代表性论文
实验室介绍

个人简历:

程冰冰博士任生物医学工程学院常任轨助理教授 (Tenure-track Assistant Professor)、研究员、博导、独立课题组组长 (Principal Investigator, PI) 和聚焦超声转化研究实验室 (Translational Research in Ultrasound THeranostics – TRUTH Lab) 主任。程博士于2016年获得美国德克萨斯大学西南医学中心 (UT Southwestern Medical Center) 和德克萨斯大学阿灵顿分校 (University of Texas at Arlington) 联合授予的生物医学工程博士学位。后于德克萨斯大学西南医学中心放射科进行以治疗聚焦超声技术及其临床转化为主的博士后研究工作。2019年受邀前往加拿大卡尔加里大学卡明医学院 (Cumming School of Medicine, University of Calgary) 和霍奇基斯脑研究所 (Hotchkiss Brain Institute) 继续博士后研究,并担任 MRgFUS Program 脑部药物递送方向的科研主管。

 

程博士长期从事生物医学工程领域中生物成像和生物治疗的基础和临床转化研究,目前已在相关领域期刊和国际会议上发表高水平学术论文和摘要50余篇,拥有美国发明专利2(已授权),并在数十次国际学术会议上作过口头报告 (Oral presentation)和受邀报告 (Invited talks)。此外程博士在美国和加拿大主持和参与了多个国家级、州/省级科研项目,获得了众多机构授予的国际学术奖项。



研究领域:

  • 聚焦超声在脑部的应用和技术研发:药物递送、热疗、神经调控

  • 超声造影剂的研发

  • 人工智能在聚焦超声中的应用


教学与课程:

生物医学信号与系统I


学术任职:

Reviewer for journals:

  • Human Brain Mapping

  • Advanced Science                                            

  • Theranostics                                                    

  • Nanotechnology                                               

  • International Journal of Hyperthermia                           

  • Annals of Biomedical Engineering                         

  • Physics in Medicine and Biology  

  • Scientific Reports                                            

  • PLOS ONE                                                        

  • IEEE Journal of Lightwave Technology                           

  • Biomedical Physics and Engineering Express                         

  • Sensors                                                    

  • Applied Sciences                                                                      

  • Journal of Current Drug Delivery


Member for associations or committees:

  • 国家科技专家库

  • 阿尔兹海默病防治协会 (China Association for Alzheimer’s Disease) 

  • International Society for Therapeutic Ultrasound (ISTU)

  • The Society for Thermal Medicine (STM)

  • Biomedical Engineering Society (BMES)

  • The Optical Society of America (OSA)

  • The International Society for Optical Engineering (SPIE)


代表性论文:

目前程博士在生物医学工程领域高水平期刊上发表 SCI 论文16篇,代表性研究成果列出如下 (#:唯一通讯作者):

  • B. Cheng#, C. Bing, T. H. Chu, S. Alzahrani, S. Pichardo, and B. G. Pike, Simultaneous localized brain mild hyperthermia and blood-brain barrier opening via feedback-controlled transcranial MR-guided focused ultrasound and microbubbles, in IEEE Transactions on Biomedical Engineering, vol. 69, no. 6, pp. 1880-1888, 2022 (Editor’s selection, Featured Article)

  • B. Cheng, C. Bing, R. M. Staruch, S. Shaikh, M. Wodzak Staruch, D. Szczepanski, N. S. Williams, T. W. Laetsch, and R. Chopra, The effect of injected dose on localized tumor accumulation and cardiac uptake of doxorubicin in a Vx2 rabbit tumor model using MR-HIFU mild hyperthermia and thermosensitive liposomes, in International Journal of Hyperthermia, vol. 37, 2020, pp. 1052-1059.

  • B. Cheng#, C. Bing, Y. Xi, B. Shah, A. A. Exner, and R. Chopra, Influence of nanobubble concentration on blood-brain barrier opening using focused ultrasound under real-time acoustic feedback control, in Ultrasound in Medicine and Biology, vol. 45, 2019, pp. 2174-2187.

  • B. Cheng, C. Bing, and R. Chopra, The effect of transcranial focused ultrasound target location on the acoustic feedback control performance during blood-brain barrier opening with nanobubbles, in Scientific Reports, vol. 9, no. 1, 2019, p. 20020.

  • B. Cheng#, Y. Chatzinoff, D. Szczepanski, C. Bing, S. Shaikh, O. Wyman, C. E. Perry, J. A. Richardson, D. K. Burns, B. M. Evers, D. E. Greenberg, and R. Chopra, Remote acoustic sensing as a safety mechanism during exposure of metal implants to alternating magnetic fields, in PLOS ONE, vol. 13, no. 5, 2018, p. e0197380.

  • B. Cheng, V. Bandi, S. Yu, F. D’Souza, K. Nguyen, Y. Hong, L. Tang, and B. Yuan, “The mechanisms and biomedical applications of an NIR BODIPY-based switchable fluorescent probe”, in International Journal of Molecular Sciences, vol. 18, no. 2, 2017, p. 384.

  • B. Cheng, V. Bandi, M-Y. Wei, Y. Pei, F. D’Souza, K. Nguyen, Y. Hong, and B. Yuan, “High-resolution ultrasound-switchable fluorescence imaging in centimeter-deep tissue phantoms with high signal-to-noise ratio and high sensitivity via novel contrast agents”, in PLOS ONE, vol. 11, no. 11, 2016, p. e0165963.

  • B. Cheng, M-Y. Wei, Y. Liu, H. Pitta, Z. Xie, Y. Hong, K. Nguyen, and B. Yuan, “Development of ultrasound-switchable fluorescence imaging contrast agents based on thermosensitive polymers and nanoparticles”, in IEEE Journal of Selected Topics in Quantum Electronics, vol. 20, no. 3, 2014, p. 6801214



论文链接:

https://scholar.google.com/citations?user=eVk6RwMAAAAJ&hl=en




实验室介绍:

聚焦超声转化研究实验室(Translational Research in Ultrasound THeranostics – TRUTH Lab)致力于研发脑疾病的无创智能精准诊疗方法和设备,包括基础、临床前转化和临床研究。研究领域属于多学科交叉,涵盖物理学、工程学、生物学、化学和医学等。课题组科研经费充足,拥有一流的科研设备和充足的实验室空间,可以给愿意加入的有志者提供良好的科研条件和研究指导。

 

实验室主要开展以下几个方面的研究工作:

  • 无创聚焦超声靶向药物递送:研发先进的聚焦超声系统并研究其在调控血脑屏障通透性中的应用。

  • 磁共振引导下的聚焦超声热疗:研究其机理和在脑疾病精准治疗中的应用。

  • 聚焦超声神经调控:研究其原理和在神经系统疾病治疗中的应用。

  • 超声造影剂的研发:研发新型纳米造影剂并研究其在超声治疗和成像中的应用。

  • 人工智能在聚焦超声中的应用:包括治疗过程优化、效果评估等。