个人简历：
Dr. Pan graduated from Xinchang High School in Zhejiang province, and received a bachelor’s degree in Bioengineering from Nanjing Agricultural University. Then Dr. Pan obtained her PhD degree in Biology from Shanghai Jiao Tong University, primarily working on the development of gene and exosome therapies for stroke and exploring their molecular mechanisms. During her postdoctoral training at Fudan University, Dr. Pan focused on investigating the risk factors leading to the rupture of brain arteriovenous malformations using techniques such as single-cell RNA sequencing. Dr. Pan has over 10 peer-reviewed articles published in journals such as Stroke and JCBFM, and she holds several grants from the National Natural Science Foundation of China as Principal Investigator or participants.
研究领域：
Basic and translational research of cerebrovascular diseases
代表性论文：
1. Pan JJ*, Qi L*, Wang L, Liu C, Song Y, Mamtilahun M, Hu X, Li Y, Chen X, Khan H, Xu Q, Wang Y, Tang Y, Yang GY, Zhang Z. M2 Microglial Extracellular Vesicles Attenuated Blood-brain Barrier Disruption via MiR-23a-5p in Cerebral Ischemic Mice. Aging Dis. 2024 May 7;15(3):1344-1356.
2. Pan J, Qu M, Li Y, Wang L, Zhang L, Wang Y, Tang Y, Tian HL, Zhang Z, Yang GY. MicroRNA-126-3p/-5p Overexpression Attenuates Blood-Brain Barrier Disruption in a Mouse Model of Middle Cerebral Artery Occlusion. Stroke. 2020 Feb;51(2):619-627.
3. Zhang LY*, Pan J*, Mamtilahun M, Zhu Y, Wang L, Venkatesh A, Shi R, Tu X, Jin K, Wang Y, Zhang Z, Yang GY. Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion. Theranostics. 2020 Jan 1;10(1):74-90.
4. Qu M*, Pan J*, Wang L, Zhou P, Song Y, Wang S, Jiang L, Geng J, Zhang Z, Wang Y, Tang Y, Yang GY. MicroRNA-126 Regulates Angiogenesis and Neurogenesis in a Mouse Model of Focal Cerebral Ischemia. Mol Ther Nucleic Acids. 2019 Jun 7;16:15-25.
5. Zhang LY*, Lin P*, Pan J*, Ma Y, Wei Z, Jiang L, Wang L, Song Y, Wang Y, Zhang Z, Jin K, Wang Q, Yang GY. CLARITY for High-resolution Imaging and Quantification of Vasculature in the Whole Mouse Brain. Aging Dis. 2018 Apr 1;9(2):262-272.
